Zentrum für interdisziplinäre Suchtforschung
der Universität Hamburg

Dr. Jakob Manthey

Wissenschaftlicher Mitarbeiter

Zentrum für Interdisziplinäre Suchtforschung (ZIS) der Universität Hamburg
c/o UKE, Klinik und Poliklinik für Psychiatrie und Psychotherapie
Martinistr. 52
20246 Hamburg

Tel.: +49 (0) 40 7410 - 59438

eMail: j.manthey@uke.de


seit 2020

Gastwissenschaftler: Universitätsklinikum Leipzig


Promotion: TU Dresden

seit 2019

Wissenschaftlicher Mitarbeiter: Zentrum für Interdisziplinäre Suchtforschung der Universität Hamburg (ZIS), Universitätsklinikum Hamburg-Eppendorf


Wissenschaftlicher Berater: WHO European Office for the prevention and control of Non-communicable Diseases, Moskau, Russland

2017 –  2021

Wissenschaftlicher Mitarbeiter am Institut für klinische Psychologie und Psychotherapie, TU Dresden

2013 – 2017

Freiberufliche Forschungsaktivitäten: TU Dresden, Centre for Addiction and Mental Health (Kanada)

2007 – 2013

Studium der Psychologie: TU Dresden (Abschluss: Dipl.-Psych.)

  • Epidemiologie von Alkohol- und Cannabiskonsum
  • Soziale und gesundheitliche Konsequenzen von Alkohol- und Cannabiskonsum
  • Evaluierung von Maßnahmen zur Reduktion der negativen Konsequenzen von Alkohol- und Cannabiskonsum
  • Verbesserung der gesundheitlichen Versorgung von Menschen mit Problemen aufgrund von Alkohol- oder Cannabiskonsum

  • Manthey J. (2024) Bewertung des Cannabisgesetzes aus einer Public Health Perspektive. Sozialpsychiatrische Informationen 2024; (2): 11-5.
  • Manthey J, Jacobsen B, Schulte B, Rehm J (2024) Rescheduling alcohol marketing bans within the World Health Organization menu of policy options. Addiction; 2024 Jun;119(6):1141-1142. doi: 10.1111/add.16476.
  • Hall W, Manthey J, Stjepanović D. (2024) Cannabis use and cannabis use disorders and their treatment in the Europe. Eur Arch Psychiatry Clin Neurosci (2024). https://doi.org/10.1007/s00406-024-01776-1
  • Manthey J. (2024) Treatment demand for cannabis use problems: analyses of routine data from 30 European countries. Eur Arch Psychiatry Clin Neurosci (2024). https://doi.org/10.1007/s00406-024-01840-w
  • Schranz A, Verthein U, Manthey J. (2024) Road safety implications of the partial legalisation of cannabis in Germany: protocol for a quasi-experimental studyBMJ Open. 2024;14:e084611. doi: 10.1136/bmjopen-2024-084611
  • Möckl J, Manthey J, Murawski M, Lindemann C, Schulte B, Reimer J, Pogarell O, Kraus L. (2024) Clustering care pathways of people with alcohol dependence using a data linkage of routine data in Bremen, Germany. BMC Med 22, 219 (2024). https://doi.org/10.1186/s12916-024-03438-4
  • Kilian C, Manthey J, Probst C. (2024) Quantifying alcohol’s harm to others: a research and policy proposal. Bulletin of the World Health Organization. Bull World Health Organ; 2024, Jun 1;102(6):448-452. doi: 10.2471/BLT.24.291338.
  • Manthey J, Rehm J, Verthein U. (2024) Germany's cannabis act: a catalyst for European drug policy reform? The Lancet Regional Health - Europe 2024;42: 100929. https://doi.org/10.1016/j.lanepe.2024.100929
  • Connor JP, Manthey J, Hall W et al. (2024) Effectiveness of cannabis use and cannabis use disorder interventions: a European and international data synthesis. Eur Arch Psychiatry Clin Neurosci . https://doi.org/10.1007/s00406-024-01829-5
  • Kilian C, Klinger S, Manthey J, Rehm J, Huckle T, Probsta C. (2024) National and regional prevalence of interpersonal violence from others’ alcohol use: a systematic review and modelling study. Lancet Reg Health Eur 2024;40: 100905. https://doi.org/10.1016/j.lanepe.2024.100905
  • Manthey J, Klinger S, Rosenkranz M, Schwarzkopf L (2024) Cannabis use, health problems, and criminal offences in Germany: national and state‑level trends between 2009 and 2021. European Archives of Psychiatry and Clinical Neuroscience. https://doi.org/10.1007/s00406-024-01778-z
  • Manthey J, Klinger S, Rosenkranz M. et al. Cannabis use, health problems, and criminal offences in Germany: national and state-level trends between 2009 and 2021. Eur Arch Psychiatry Clin Neurosci (2024). https://doi.org/10.1007/s00406-024-01778-z
  • Manthey J, Gobiņa I, Isajeva L, Neneman J, Reile R, Štelemėkas M, Rehm J (2024) The Impact of Raising Alcohol Taxes on Government Tax Revenue: Insights from Five European Countries. Appl Health Econ Health Policy . https://doi.org/10.1007/s40258-024-00873-5
  • Obradors-Pineda A, Bouso J C, Colom J, Manthey J (2024) Who is in, for How Long and What for. Exploring the Social Dimension of Cannabis Social Clubs in Barcelona, 2017-2020. Journal of Drug Issues, 0(0). https://doi.org/10.1177/00220426231226222
  • Kotz D, Kastaun S, Manthey J, Hoch E, Klosterhalfen S (2024) Cannabisgebrauch in Deutschland. Häufigkeit, Administrationswege und gemeinsame Nutzung von inhalierten Nikotin- und Tabakprodukten. Dtsch Arztebl Int 2024; 121: 52-7; DOI: 10.3238/arztebl.m2023.0237
  • Manthey J, Jacobsen B, Klinger S, Schulte B, Rehm J (2023) Restricting alcohol marketing to reduce alcohol consumption: A systematic review of the empirical evidence for one of the ‘best buys’. Addiction. https://doi.org/10.1111/add.16411
  • Kilian C, Rehm J, Shield K, Manthey J (2023) Changes in Alcohol-Specific Mortality During the COVID-19 Pandemic in 14 European Countries. SUCHT 2023 69:6, 285-293. doi.org/10.1024/0939-5911/a000841
  • Olderbak S, Möckl J, Manthey J, Lee S, Rehm J, Hoch E, Kraus L (2023) Trends and projection in the proportion of (heavy) cannabisuse in Germany from 1995 to 2021. Addiction. 2023;1–11
  • Rehm J, Badaras R, Ferreira-Borges C, Galkus L, Gostautaite Midttun N, Gobiņa I, Janik-Koncewicz K, Manthey J et al. (2023) Impact of the WHO "best buys" for alcohol policy on consumption and health in the Baltic countries and Poland 2000–2020; The Lancet Regional Health - Europe, 2023, 100704, ISSN 2666-7762, https://doi.org/10.1016/j.lanepe.2023.100704.
  • Kraus L, Kilian C, Manthey J, Rehm J. (2023) Alkoholpolitik in Deutschland, Österreich und der Schweiz? SUCHT. 2023;69(4):145-6
  • Kilian C, Manthey J, Rehm J, Kraus L. (2023) Alkoholpolitik in Deutschland: Verpasste Chancen zur Senkung der Krankheitslast. SUCHT. 2023;69(4):163-71.
  • Manthey J, Armstrong MJ, Hayer T, Myran DT, Pacula RL, Queirolo R, et al. (2023) How to interpret studies on the impact of legalizing cannabis. Addiction. https://doi.org/10.1111/add.16314
  • Kilian C, Carr S, Schulte B, Manthey J (2023) Increased alcohol-specific mortality in Germany during COVID-19: State-level trends from 2010 to 2020. Drug Alcohol Rev;42(3):633-640. doi: 10.1111/dar.13573.
  • Manthey J, Kilian C, Schäfer I, Wirth M, Schulte B (2023) Changes in the alcohol-specific disease burden during the COVID-19 pandemic in Germany: interrupted time series analyses. European journal of public health. doi:10.1093/eurpub/ckad103
  • Kilian C, Manthey J, Moskalewicz J, Braddick F, Matrai S, López-Pelayo H, et al. (2023) The socioeconomic profile of alcohol use in Europe: Findings from a cross-sectional survey of 33 European countries. International Journal of Alcohol and Drug Research. 2023;11(1):13-23
  • Kilian C, Manthey J, Braddick F, López-Pelayo H, Rehm J. (2023) Social disparities in alcohol's harm to others: evidence from 32 European countries. International Journal of Drug Policy. 2023;118:104079
  • Manthey J, Obradors-Pineda A. (2023) Prices of flower and resin in cannabis social clubs: Analyses of register data from 220,000 collections. Drug Alcohol Rev. 2023. DOI: https://doi.org/10.1111/dar.13680
  • Manthey J, Kokole D, Riedel-Heller S, Rowlands G, Schäfer I, Schomerus G, et al. (2023) Improving alcohol health literacy and reducing alcohol consumption: recommendations for Germany. Addict Sci Clin Pract. 2023;18(1):28. DOI: 10.1186/s13722-023-00383-0
  • Solovei, A., Rovira, P., Anderson, P., Jané-Llopis, E., Natera Rey, G., Arroyo, M., Medina, P., Mercken, L., Rehm, J., de Vries, H., & Manthey, J. (2023) Improving alcohol management in primary health care in Mexico: A return-on-investment analysis. Drug and Alcohol Review, 42(3), 680-690. https://doi.org/10.1111/dar.13598
  • Manthey, J., Jacobsen, B., Hayer, T., Kalke, J., López-Pelayo, H., Pons-Cabrera, M. T., Verthein, U., Rosenkranz, M. (2023) The impact of legal cannabis availability on cannabis use and health outcomes: A systematic review. International Journal of Drug Policy, 116, 104039. https://doi.org/10.1016/j.drugpo.2023.104039
  • Manthey J, Braddick F, López-Pelayo H, Shield K, Rehm J, Kilian C. (2023) Unrecorded alcohol use in 33 European countries: Analyses of a comparative survey with 49,000 people who use alcohol. International Journal of Drug Policy, 116, 104028. https://doi.org/https://doi.org/10.1016/j.drugpo.2023.104028
  • Kim, K. V., Rehm, J., Feng, X., Jiang, H., Manthey, J., Radišauskas, R., Štelemėkas, M., Tran, A., Zafar, A., Lange, S. (2023) Impacto de políticas de control de alcohol en las tasas de mortalidad por ictus hemorrágico e isquémico en Lituania: Análisis de series temporales interrumpidas. 2023. https://doi.org/10.20882/adicciones.1828
  • Manthey J, Pons-Cabrera M T, Rosenkranz M, Lopez-Pelayo H (2023) Measuring cannabis quantities in online surveys: A rapid review and proposals for ways forward. International Journal of Methods in Psychiatric Research, e1971. https://doi.org/10.1002/mpr.1971
  • Kilian C, Klinger S, Rehm J, Manthey J. (2023) Alcohol use, dementia risk, and sex: a systematic review and assessment of alcohol-attributable dementia cases in Europe. BMC Geriatrics volume 23, Article number: 246 (2023). https://doi.org/10.1186/s12877-023-03972-5
  • Kalke J, Jacobsen B, Hayer T, Rosenkranz M, Verthein U & Manthey J. (2023) Handlungsempfehlungen zur Legalisierung von Cannabis in Deutschland. Kinder- und Jugendschutz in Wissenschaft und Praxis 2023; 68 (2): 49-53
  • Rehm J, Rovira P, Manthey J, Anderson P (2023) Reduction of Alcoholic Strength: Does It Matter for Public Health? Nutrients; 15:910
  • Manthey J, Jasilionis D, Jiang H, Meščeriakova O, Petkevičienė J, Radišauskas R, Štelemėkas M, Rehm J (2023) The impact of alcohol taxation increase on all-cause mortality inequalities in Lithuania: an interrupted time series analysis. BMC Med, 16;21:22. doi: 10.1186/s12916-022-02721-6
  • Manthey J (2023) Harm Reduction und Cannabis: Was ändert sich durch die Legalisierung? Sucht, 69: 4-8. https://doi.org/10.1024/0939-5911/a000798.
  • Manthey J (2023) Welchen Beitrag leistet die Wissenschaft in der deutschen Debatte um die Cannabislegalisierung? Sucht, 69: 1-3. https://doi.org/10.1024/0939-5911/a000797
  • Möckl J, Lindemann C, Manthey J, Schulte B, Reimer J, Pogarell O, Kraus, L (2023) Estimating the prevalence of alcohol-related disorders and treatment utilization in Bremen 2016/2017 through routine data linkage. Frontiers in Psychiatry, 14. https://doi.org/10.3389/fpsyt.2023.1002526
  • Kilian C, Carr S, Schulte B, Manthey J (2022) Increased alcohol-specific mortality in Germany during COVID-19: State-level trends from 2010 to 2020. Drug and Alcohol Review, 42(3), 633-640. https://doi.org/10.1111/dar.13573
  • Kilian C, Manthey J, Neufeld M, Rehm J. (2023) Affordability of Alcoholic Beverages in the European Union. European Addiction Research, 29(1), 63-66. https://doi.org/10.1159/000527096
  • Lange, S., Jiang, H., Štelemėkas, M., Tran, A., Cherpitel, C., Giesbrecht, N., Gostautaite Midttun, N., Jasilionis, D., Kaplan, M. S., Manthey, J., Xuan, Z., & Rehm, J. (2023) Evaluating the Impact of Alcohol Policy on Suicide Mortality: A Sex-Specific Time-Series Analysis for Lithuania. Arch Suicide Res, 27(2), 339-352. https://doi.org/10.1080/13811118.2021.1999873
  • Jürgen Rehm, Shannon Lange, Inese Gobiņa, Kinga Janik-Koncewicz, Laura Miščikienė, Rainer Reile, Relika Stoppel, Alexander Tran, Carina Ferreira-Borges, Domantas Jasilionis, Huan Jiang, Kawon Victoria Kim, Jakob Manthey, Maria Neufeld, Janina Petkevičienė, Ričardas Radišauskas, Robin Room, Vaida Liutkutė-Gumarov, Witold A. Zatoński, Mindaugas Štelemėkas (2022) Classifying alcohol control policies between 2000 and 2020 in Poland and the Baltic countries to model potential impact. Addiction, First published: 05 December 2022. doi.org/10.1111/add.16102
  • Manthey J, Verthein U. (2022) Plädoyer für eine evidenzbasierte Legalisierung von Cannabis. SUCHT. 2022;68(6):351-8
  • Jiang H, Feng X, Lange S, Tran A, Manthey J, Rehm J (2022) Estimating effects of health policy interventions using interrupted time-series analyses: a simulation study. BMC Med Res Methodol. 2022;22(1):235
  • Allamani A, Voller F, Bravi S, Pepe P, Biffino M, Buscema PM, et al. (2022) Alcohol Addiction: One Entity or Different Entities? A DSM-4-Based Attempt Toward a Geographicization of Alcohol Addiction and Abuse. Alcohol Alcohol. 2022:agac021
  • Manthey J, Carr S, Klinger S (2022) Estimaciones del impacto del consumo de cannabis en la salud y principales indicadores de daño individual y social relacionados con el consumo de cannabis. 2022. In: GUÍA CLÍNICA DE CANNABIS [Internet]. Socidrogalcohol. Available from: https://socidrogalcohol.org/wp-content/uploads/2022/01/guia-cannabis_original-maquetada_compressed.pdf
  • Carr S, Manthey J, Klinger S (2022) Desafíos para la epidemiología en la evaluación del consumo de cànnabis. 2022. In: GUÍA CLÍNICA DE CANNABIS [Internet]. Socidrogalcohol. Available from: https://socidrogalcohol.org/wp-content/uploads/2022/01/guia-cannabis_original-maquetada_compressed.pdf
  • Manthey J, Benegal V, Kilian C, Mahadevan J, Mejía-Trujillo J, Morojele N, et al. (2022) International Perspectives on Stigma toward People with Substance Use Disorders. In: Schomerus G, Corrigan PW, editors. The Stigma of Substance Use Disorders. Cambridge: Cambridge University Press; 2022. p. 107-43
  • Lorenzetti V, Hindocha C, Petrilli K, Griffiths P, Brown J, Castillo-Carniglia Á, et al. (2022) The iCannToolkit: a tool to embrace measurement of medicinal and non-medicinal cannabis use across licit, illicit and cross-cultural settings. Addiction. 2022;117(6):1523-5
  • Lorenzetti V, Hindocha C, Petrilli K, Griffiths P, Brown J, Castillo-Carniglia Á, et al. (2022) The iCannTookit: a consensus-based, flexible framework for measuring contemporary cannabis use. Addiction. 2022;117(9):2558-60
  • Manthey J. (2022) Legalisierung von Cannabis: Preise spielen eine zentrale Rolle. Deutsches Ärzteblatt. 2022;119(13):A-562 / B-464
  • Kummetat JL, Leonhard A, Manthey J, Speerforck S, Schomerus G (2022) Understanding the Association between Alcohol Stigma and Alcohol Consumption within Europe: A Cross-Sectional Exploratory Study. Eur Addict Res. 2022
  • Rastogi A, Manthey J, Wiemker V, Probst C (2022) Alcohol consumption in India: a systematic review and modelling study for sub-national estimates of drinking patterns. Addiction. 2022;117(7):1871-86
  • Rehm J, Donnell A, Kaner EFS, Jane Llopis E, Manthey J, Anderson P (2022) Differential impact of minimum unit pricing on alcohol consumption between Scottish men and women: controlled interrupted time series analysis. BMJ Open. 2022;12(7):e054161
  • Carr S, Lindemann C, Kraus L, Rehm J, Schulte B, Manthey J (2022) Alcohol Consumption Levels and Health Care Utilization in Germany. SUCHT;68:151-60
  • Frischknecht U, Hoffmann S, Steinhauser A, Lindemann C, Buchholz A, Manthey J, Schulte B, Rehm J, Kraus L, Verthein U, Reimer J, Kiefer F (2022) Screening auf problematischen Alkoholkonsum – Erhebung zur Umsetzung der S3-Leitlinienempfehlungen in der transdisziplinären Versorgung einer Modellregion. Gesundheitswesen; 84(1):43-51. doi: 10.1055/a-1276-0475
  • Bloomfield K, Kilian C, Manthey J, Rehm J, Brummer J, Grittner U (2022) Changes in Alcohol Use in Denmark during the Initial Months of the COVID-19 Pandemic: Further Evidence of Polarization of Drinking Responses. Eur Addict Res; 21:1-12. doi: 10.1159/000524379
  • Kilian C, Neufeld M, Manthey J, Alavidze S, Bobrova A, Baron-Epel O, Berisha M, Bilici R, Davletov K, Isajeva L, Kantaş Yılmaz F, Karatkevich T, Mereke A, Musić Milanović S, Galstyan K, Muslić L, Okoliyski M, Shabani Z, Štelemėkas M, Sturua L, Sznitman SR, Ünübol B, Ferreira-Borges C, Rehm J (2022) Self-reported changes in alcohol and tobacco use during COVID-19: findings from the eastern part of WHO European Region. Eur J Public Health: ckac011. doi: 10.1093/eurpub/ckac011
  • Kilian C, Rovira P, Neufeld M, Manthey J, Rehm J (2022) Potenzielle Auswirkungen erhöhter Alkoholsteuern auf die alkoholbedingte Krankheitslast in Deutschland: Eine Modellierungsstudie. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. doi: 10.1007/s00103-022-03528-9
  • Lorenzetti V, Hindocha C, Petrilli K, Griffiths P, Brown J, Castillo-Carniglia Á, Caulkins JP, Englund A, ElSohly MA, Gage SH, Groshkova T, Gual A, Hammond D, Lawn W, López-Pelayo H, Manthey J, Mokrysz C, Pacula RL, van Laar M, Vandrey R, Wadsworth E, Winstock A, Hall W, Curran HV, Freeman TP (2022) The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use. Addiction; 117(6):1510-1517. First published: 29 September 2021. doi: 10.1111/add.15702
  • Schomerus G, Leonhard A, Manthey J, Morris J, Neufeld M, Kilian C, Speerforck S, Winkler P, Corrigan PW (2022) The stigma of alcohol-related liver disease and its impact on healthcare. J Hepatol; S0168-8278(22)00262-8. doi: 10.1016/j.jhep.2022.04.026
  • Zafar A, Rehm J, Feng X, Jiang H, Kim KV, Manthey J, Radišauskas R, Štelemėkas M, Petkevičienė J, Tran A, Lange S (2022) The Impact of Alcohol Control Policy on Pneumonia Mortality in Lithuania: An Interrupted Time-Series Analysis. Epidemiol Infect; 1-25. doi: 10.1017/S0950268822000711
  • Tran A, Jiang H, Lange S, Manthey J, Štelemėkas M, Badaras R, Petkevičienė J, Radišauskas R, Room R, Rehm J (2022) Can alcohol control policies reduce cirrhosis mortality? An interrupted time-series analysis in Lithuania. Liver Int; 42:765-774. doi: 10.1111/liv.15151
  • Manthey J, Carr S, Anderson P, Bautista N, Braddick F, O'Donnell A, Jané-Llopis E, López-Pelayo H, Medina P, Mejía-Trujillo J, Pérez-Gómez A, Piazza M, Rehm J, Solovei A, Rey GN, de Vries H, Schulte B (2022) Reduced alcohol consumption during the COVID-19 pandemic: Analyses of 17 000 patients seeking primary health care in Colombia and Mexico. J Glob Health; 12:05002. doi: 10.7189/jogh.12.05002
  • Solovei A, Manthey J, Anderson P, Mercken L, Jané Llopis E, Natera Rey G, Pérez Gómez A, Mejía Trujillo J, Bustamante I, Piazza M, Pérez de León A, Arroyo M, de Vries H, Rehm J, Evers S (2022) Costs of an Alcohol Measurement Intervention in Three Latin American Countries. Int J Environ Res Public Health; 19:700. doi: 10.3390/ijerph19020700
  • Kilian C, O'Donnell A, Potapova N, López-Pelayo H, Schulte B, Miquel L, Paniello Castillo B, Schmidt CS, Gual A, Rehm J, Manthey J (2022) Changes in alcohol use during the COVID-19 pandemic in Europe: A meta-analysis of observational studies. Drug Alcohol Rev; 41:918-931. doi: 10.1111/dar.13446
  • Llamosas-Falcón L, Manthey J, Rehm J (2022) Changes in alcohol consumption in Spain between 1990 and 2019. Adicciones; 16:61-72
  • Manthey J, Jasilionis D, Jiang H, Mesceriakova-Veliuliene O, Petkeviciene J, Radisauskas R, Rehm J, Stelemekas M (2021) Interrupted time series analyses to assess the impact of alcohol control policy on socioeconomic inequalities in mortality in Lithuania: a study protocol. BMJ Open, 6;11:e053497
  • Frischknecht U, Hoffmann S, Steinhauser A, Lindemann L, Buchholz A, Manthey J, Schulte B, Rehm J, Kraus L, Verthein U, Reimer J, Kiefer F (2021) Diagnostik und Behandlung alkoholbezogener Störungen – Versorgerbefragung zur Erarbeitung von Strategien der Leitlinienimplementierung. Suchttherapie; 22: 141 - 151. DOI 10.1055/a-1265-4687
  • Kalke J, Manthey J, Rosenkranz M, Rehm J & Verthein U (2021) Wie sollte ein Modellversuch zur kontrollierten Abgabe von Cannabis aus Sicht der Konsument*innen ausgestaltet sein? Ergebnisse einer Befragung aus Berlin. In: akzept e. V. Bundesverband, Hrsg. 8. Alternativer Drogen- und Suchtbericht. Lengerich: Pabst Science Publishers 163-171
  • Manthey J, Solovei A, Anderson P, Carr S, Rehm J (2021) Can alcohol consumption in Germany be reduced by alcohol screening, brief intervention and referral to treatment in primary health care? Results of a simulation study. PLoS One, 5;16(8):e0255843. doi: 10.1371/journal.pone.0255843 
  • López-Pelayo H, Campeny E, Oliveras C, Rehm J, Manthey J, Gual A, Balcells-Olivero MLM (2021) Early, Chronic, and Acute Cannabis Exposure and Their Relationship With Cognitive and Behavioral Harms. Front Psychiatry, 9;12:643556. doi: 10.3389/fpsyt.2021.643556 
  • Tran A, Manthey J, Lange S, Jiang H, Štelem?kas M, Liutkut?-Gumarov V, Meš?eriakova-Veliulien? O, Petkevi?ien? J, Radišauskas R, Telksnys T, Rehm J (2021) Alcohol control policies add to secular trends in all-cause mortality rates in young adults. Sci Rep, 23;11(1):15127. doi: 10.1038/s41598-021-94562-1
  • Caballeria E, López-Pelayo H, Segura L, Wallace P, Oliveras C, Díaz E, Manthey J, Baena B, Colom J, Gual A & EFAR group (2021) A randomized controlled non-inferiority trial of primary care-based facilitated access to an alcohol reduction website (EFAR Spain). Internet Interv; 26:100446
  • López-Pelayo H, Campeny E, Oliveras C, Rehm J, Manthey J, Gual A, Balcells-Olivero MLM (2021) Early, Chronic, and Acute Cannabis Exposure and Their Relationship With Cognitive and Behavioral Harms. Front Psychiatry;12:643556. doi: 10.3389/fpsyt.2021.643556
  • O'Donnell A, Schulte B, Manthey J, Schmidt CS, Piazza M, Chavez IB, Natera G, Aguilar NB, Hernández GYS, Mejía-Trujillo J, Pérez-Gómez A, Gual A, de Vries H, Solovei A, Kokole D, Kaner E, Kilian C, Rehm J, Anderson P, Jané-Llopis E (2021) Primary care-based screening and management of depression amongst heavy drinking patients: Interim secondary outcomes of a three-country quasi-experimental study in Latin America. PLoS One, 5;16. doi: 10.1371/journal.pone.0255594
  • Lopez-Pelayo H, Matrai S, Balcells-Olivero M, Campeny E, Braddick F, Bossong M, Cruz OS, Deluca P, Dom G, Feingold D, Freeman TP, Guzman P, Hindocha BC, Kelly N, Liebregts N, Lorenzetti V, Manthey J, Matias J, Oliveras C, Pons MT, Rehm J, Rosenkranz M, Swithenbank Z, van Deurse L, Vicente J, Vuolo M, Wojnar M, Gual A (2021) Standard units for cannabis dose: Why is it important to standardize cannabis dose for drug policy and how can we enhance its place on the public health agenda? International Journal of Drug Policy, 97, 103350
  • Kilian C, Rehm J, Allebeck P, Braddick F, Gual A, Barták M, Bloomfield K, Gil A, Neufeld M, O'Donnell A, Petruželka B, Rogalewicz V, Schulte B, Manthey J, the European Study Group on Alcohol Use and COVID-19 (2021) Alcohol consumption during the COVID-19 pandemic in Europe: a large-scale cross-sectional study in 21 countries. Addiction, https://doi.org/10.1111/add.15530
  • López-Pelayo H, Matrai S, Balcells-Olivero M, Campeny E, Braddick F, Bossong MG, Cruz OS, Deluca P, Dom G, Feingold D, Freeman TP, Guzman P, Hindocha C, Kelly BC, Liebregts N, Lorenzetti V, Manthey J, Matias J, Oliveras C, Pons MT, Rehm J, Rosenkranz M, Swithenbank Z, van Deurse L, Vicente J, Vuolo M, Wojnar M and Gual A (2021) Supporting Future Cannabis Policy – Developing a Standard Joint Unit: A Brief Back-Casting Exercise. Frontiers in Psychiatry; 12(606)
  • Kilian C, Rehm J, Allebeck P, Barták M, Braddick F, Gual A, Matrai S, Petruželka B, Rogalewicz V, Rossow I, Schulte B, Štelemekas M, Manthey J (2021) Conducting a multi-country online alcohol survey in the time of the COVID-19 pandemic: Opportunities and challenges. Int J Methods Psychiatr Res. doi: 10.1002/mpr.1875
  • Chrystoja BR, Rehm J, Manthey J, Probst C, Wettlaufer A, Shield KD (2021) A systematic comparison of the global comparative risk assessments for alcohol. Addiction. doi: 10.1111/add.15413
  • Llamosas-Falcón L, Shield KD, Gelovany M, Hasan OSM, Manthey J, Monteiro M, Walsh N, Rehm J (2021) Impact of alcohol on the progression of HCV-related liver disease: A systematic review and meta-analysis. J Hepatol. 20, doi: 10.1016/j.jhep.2021.04.018
  • Rehm J, Štelemekas M, Ferreira-Borges C, Jiang H, Lange S, Neufeld M, Room R, Casswell S, Tran A, Manthey J (2021) Classifying Alcohol Control Policies with Respect to Expected Changes in Consumption and Alcohol-Attributable Harm: The Example of Lithuania, 2000-2019. Int J Environ Res Public Health. 2;18(5):2419. doi: 10.3390/ijerph18052419
  • Stelemekas M, Manthey J, Badaras R, Casswell S, Ferreira-Borges C, Kalediene R, Lange S, Neufeld M, Petkeviciene J, Radišauskas R, Room R, Telksnys T, Zurlyte I, Rehm J (2021) Alcohol control policy measures and all-cause mortality in Lithuania: an interrupted time-series analysis. Addiction. 2021 doi: 10.1111/add.15470
  • Anderson P, O'Donnell A, Kaner E, Llopis EJ, Manthey J, Rehm J (2021) Impact of minimum unit pricing on alcohol purchases in Scotland and Wales: controlled interrupted time series analyses. Lancet Public Health. doi: 10.1016/S2468-2667(21)00052-9
  • Manthey J, Kilian C, Carr S, Allebeck P, Braddick F, Gual A, Barták M, Bloomfield K, Gil A, Neufeld M, O’Donnell A, Petruželka B, Rogalewicz V, Schulte B, Rehm J (2021) Use of alcohol, tobacco, cannabis, and other substances during the first wave of the SARS-CoV-2 pandemic in Europe: a survey on 36,000 European substance users. Subst Abuse Treat Prev Policy 16, 36. https://doi.org/10.1186/s13011-021-00373-y
  • Kilian C, Manthey J, Carr S, Hanschmidt F, Rehm J, Speerforck S, Schomerus S (2021) Stigmatisation of people with alcohol use disorders: an updated systematic review of population studies. Alcoholism: Clinical and Experimental Research. doi: 10.1111/acer.14598
  • Manthey J, Hassan SA, Carr S, Kilian C, Kuitunen-Paul S, Rehm J (2021) What are the economic costs to society attributable to alcohol use? A systematic review and modelling study. PharmacoEconomics. doi: 10.1007/s40273-021-01031-8
  • Manthey J, Hassan SA, Carr S, Kilian C, Kuitunen-Paul S, Rehm J (2021) Estimating the economic consequences of substance use and substance use disorders. Expert Review of Pharmacoeconomics & Outcomes Research. doi: 10.1080/14737167.2021.1916470
  • Bruguera P, Barrio P, Manthey J, Oliveras C, López-Pelayo H, Nuño L, Miquel L, López-Lazcano A, Blithikioti C, Caballeria E, Matrai S, Rehm J, Vieta E, Gual A (2021) Mid and long-term effects of a SBIRT program for at-risk drinkers attending to an emergency department. Follow-up results from a randomized controlled trial. Eur J Emerg Med. doi: 10.1097/MEJ.0000000000000810
  • Llamosas-Falcón L, Shield KD, Gelovany M, Hasan OSM, Manthey J, Monteiro M, Walsh N, Rehm J (2021) Impact of alcohol on the progression of HCV-related liver disease: A systematic review and meta-analysis. J Hepatol. doi: 10.1016/j.jhep.2021.04.018
  • Carr S, Rehm J, Manthey J (2021) Guidelines and reality in studies on the economic costs of alcohol use: a systematic review. The International Journal of Alcohol and Drug Research. https://doi.org/10.7895/ijadr.283
  • Kokole D, Mercken L, Jané-Llopis E, Natera Rey G, Arroyo M, Medina P, Pérez-Gómez A, Mejía-Trujillo J, Piazza M, Bustamante IV, O'Donnell A, Kaner E, Gual A, Lopez-Pelayo H, Schulte B, Manthey J, Rehm J, Anderson P, de Vries H (2021) Perceived appropriateness of alcohol screening and brief advice programmes in Colombia, Mexico and Peru and barriers to their implementation in primary health care - a cross-sectional survey. Prim Health Care Res Dev, 28;22:e4. doi: 10.1017/S1463423620000675
  • Anderson P, Manthey J, Llopis EJ, Rey GN, Bustamante IV, Piazza M, Aguilar PSM, Mejía-Trujillo J, Pérez-Gómez A, Rowlands G, Lopez-Pelayo H, Mercken L, Kokole D, O'Donnell A, Solovei A, Kaner E, Schulte B, de Vries H, Schmidt C, Gual A, Rehm J. (2021) Impact of Training and Municipal Support on Primary Health Care-Based Measurement of Alcohol Consumption in Three Latin American Countries: 5-Month Outcome Results of the Quasi-experimental Randomized SCALA Trial. J Gen Intern. doi: 10.1007/s11606-020-06503-9
  • Kilian C, Manthey J, Kraus L, Mäkelä P, Moskalewicz J, Sieroslawski J, Rehm J (2021) A new perspective on European drinking cultures: a model-based approach to determine variations in drinking practices among 19 European countries. Addiction. doi: 10.1111/add.15408
  • Loy JK, Seitz NN, Bye EK, Dietze P, Kilian C, Manthey J, Raitasalo K, Soellner R, Trolldal B, Törrönen J, Kraus L (2021) Changes in Alcoholic Beverage Choice and Risky Drinking among Adolescents in Europe 1999-2019. Int J Environ Res Public Health; 18;18(20):10933
  • Rossow I, Bartak M, Bloomfield K, Braddick F, Bye EK, Kilian C, López-Pelayo H, Mäkelä P, Moan IS, Moskalewicz J, Petruzelka B, Rogalewicz V, Manthey J (2021) Changes in Alcohol Consumption during the COVID-19 Pandemic Are Dependent on Initial Consumption Level: Findings from Eight European Countries. Int J Environ Res Public Health;18:10547
  • Manthey J, Freeman TP, López-Pelayo H, Rehm J (2021) Public health monitoring of cannabis use in Europe: prevalence of use, cannabis potency, and treatment rates. The Lancet Regional Health – Europe. doi:https://doi.org/10.1016/j.lanepe.2021.100227
  • Manthey J, Lindemann C, Kraus L, Reimer J, Verthein U, Schulte B, Rehm J (2020) The potential effects of an extended alcohol withdrawal treatment programme on morbidity and mortality among inpatients in the German city of Bremen: a simulation study. Subst Abuse Treat Prev Policy; 2:15. doi: 10.1186/s13011-019-0249-7
  • Manthey J, Lindemann C, Verthein U, Frischknecht U, Kraus L, Reimer J, Grün A, Kiefer F, Schulte B, Rehm J (2020) Versorgung von Personen mit riskantem Alkoholkonsum und schwerer Alkoholkonsumstörung in Bremen: bedarfsgerecht und leitlinienkonform? Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz; 63:122-130. doi: 10.1007/s00103-019-03072-z
  • Shield K, Manthey J, Rylett M, Probst C, Wettlaufer A, Parry C, Rehm J (2020) National, regional, and global burdens of disease from 2000 to 2016 attributable to alcohol use: a comparative risk assessment study. The Lancet Public Health. 5. doi: 10.1016/S2468-2667(19)30231-2.
  • Manthey J, Kilian C, Schomerus G, Kraus L, Rehm J, Schulte B (2020) Veränderungen im Alkoholkonsum in Deutschland und Europa während des (bisherigen) Höhepunkts der SARS-CoV-2 Pandemie. SUCHT, 66, 1–12
  • Manthey J, Kalke J, Rehm J, Rosenkranz M, Verthein U (2020) Controlled administration of cannabis to mitigate cannabis-attributable harm among recreational users: a quasi-experimental study in Germany. F1000Res; 9: 201. doi: 10.12688/f1000research.22612.1
  • Schulte B, Schmidt CS, Manthey J, Strada L, Christensen S, Cimander K, Görne H, Khaykin P, Scherbaum N, Walcher S, Mauss S, Schäfer I, Verthein U, Rehm J,  Reimer J (2020) Clinical and Patient-Reported Outcomes of Direct-Acting Antivirals for the Treatment of Chronic Hepatitis C Among Patients on Opioid Agonist Treatment: A Real-world Prospective Cohort Study. Open Forum Infectious Diseases, https://doi.org/10.1093/ofid/ofaa317
  • Rehm J, Kilian C, Rovira P, Shield KD, Manthey J (2020) The elusiveness of representativeness in general population surveys for alcohol Drug Alcohol Rev. doi:10.1111/dar.13148
  • Jané-Llopis E, Anderson P, Piazza M, O'Donnell A, Gual A, Schulte B, Pérez Gómez A, de Vries H,  Natera Rey G, Kokole D, Bustamante I, Braddick F, Mejía Trujillo J, Solovei A, Pérez De León A, Kaner E, Matrai S, Manthey J, Mercken L, López-Pelayo H, Rowlands G, Schmidt C, Rehm J (2020) Implementing primary healthcare-based measurement, advice and treatment for heavy drinking and comorbid depression at the municipal level in three Latin American countries: final protocol for a quasiexperimental study (SCALA study). BMJ Open, http://dx.doi.org/10.1136/bmjopen-2020-038226
  • Rehm J, Manthey J (2020) Cannabis and public health: a global experiment without control. World Psychiatry. 19:192-194. doi:10.1002/wps.20740
  • Llamosas-Falcón L, Shield KD, Gelovany M, Manthey J, Rehm J (2020) Alcohol use disorders and the risk of progression of liver disease in people with hepatitis C virus infection – a systematic review. Subst Abuse Treat Prev Policy. 2020 Jun 30;15(1):45. doi: 10.1186/s13011-020-00287-1
  • Rehm J, Kilian C, Ferreira-Borges C, Jernigan D, Monteiro M, Parry CDH, Sanchez ZM, Manthey J (2020) Alcohol use in times of the COVID 19: Implications for monitoring and policy. Drug Alcohol Rev. 2020 May;39(4):301-304. doi: 10.1111/dar.13074
  • Sornpaisarn B, Shield K, Manthey J, Limmade Y, Low WY, Van Thang V, Rehm J (2020) Alcohol consumption and attributable harm in middle-income South-East Asian countries: Epidemiology and policy options. Int J Drug Policy. 2020 Jul 22;83:102856. doi: 10.1016/j.drugpo.2020.102856
  • Probst C, Manthey J, Neufeld M, et al. (2020) Meeting the Global NCD Target of at Least 10% Relative Reduction in the Harmful Use of Alcohol: Is the WHO European Region on Track?. Int J Environ Res Public Health. 17:3423. doi:10.3390/ijerph17103423
  • Manthey J, Carr S, Rehm J (2020) Definition of a 'standard joint equivalent': Comment on "Who consumes most of the cannabis in Canada? Profiles of cannabis consumption by quantity". Drug Alcohol Depend, 1;206:107731. doi: 10.1016/j.drugalcdep.2019.107731
  • Kilian C, Manthey J, Probst C, et al. (2020) Why Is Per Capita Consumption Underestimated in Alcohol Surveys? Results from 39 Surveys in 23 European Countries. Alcohol Alcohol. 55:554-563. doi:10.1093/alcalc/agaa048
  • Manthey J, Probst C, Kilian C, Moskalewicz J, Sieros?awski J, Karlsson T, Rehm J (2020) Unrecorded Alcohol Consumption in Seven European Union Countries. Eur Addict Res. doi: 10.1159/000506333
  • Rehm J, Crépault JF, Wettlaufer A, Manthey J, Shield K (2020) What is the best indicator of the harmful use of alcohol? A narrative review. Drug Alcohol Rev. doi: 10.1111/dar.13053
  • Schulte B, Lindemann C, Buchholz A, Rosahl A, Härter M, Kraus L, Kiefer F, Frischknecht U, Hoffmann S, Wensing M, O'Donnell A, Manthey J, Rehm J, Schäfer I, Verthein U, Reimer J (2019) Tailored interventions to support the implementation of the German national guideline on screening, diagnosis and treatment of alcohol-related disorders: a project protocol. SUCHT; 65: 373-381
  • Kilian C, Manthey J, Moskalewicz J, Sieroslawski J, Rehm J (2019) How Attitudes toward Alcohol Policies Differ across European Countries: Evidence from the Standardized European Alcohol Survey (SEAS). Int. J Environ Res Public Health; 16: 4461. doi:10.3390/ijerph16224461
  • O'Donnell A, Anderson P, Jané-Llopis E, Manthey J, Kaner E, Rehm J (2019) Immediate impact of minimum unit pricing on alcohol purchases in Scotland: controlled interrupted time series analysis for 2015-18. BMJ; 25:366 doi:10.1136/bmj.l5274
  • Rehm J, Elton-Marshall T, Sornpaisarn B, Manthey J (2019) Medical marijuana. What can we learn from the experiences in Canada, Germany and Thailand? Int J Drug Policy; 13:74:47-51. doi: 10.1016/j.drugpo.2019.09.001
  • Rehm J, Manthey J, Lange S, Badaras R, Zurlyte I, Passmore J, Breda J,Ferreira-Borges C, Štelem?kas M (2019) Alcohol control policy and changes inalcohol-related traffic harm. Addiction. doi: 10.1111/add.14796
  • Manthey J, Rehm J (2019) Mortality from Alcoholic Cardiomyopathy: Exploring the Gap between Estimated and Civil Registry Data. J Clin Med; 31: 8. doi:10.3390/jcm8081137
  • Manthey J, Rehm J (2019) Mortality from Alcoholic Cardiomyopathy: Exploring the Gap between Estimated and Civil Registry Data. J Clin Med. 31;8. doi: 10.3390/jcm8081137
  • Manthey J (2019) Cannabis use in Europe: Current trends and public health concerns. International Journal of Drug Policy; 68, 93-96
  • Ye Y, Shield KD, Cherpitel CJ, Manthey J, Korcha R, Rehm J (2018) Estimating alcohol-attributable fractions for injuries based on data from emergency department and observational studies: a comparison of two methods. Addiction, 114, 462-70. doi: 10.1111/add.14477 
  • Miquel L, Manthey J, Rehm J, Vela E, Bustins M, Segura L, Vieta E, Colom J, Anderson P, Gual A (2018) Risky alcohol use: The impact on health service use. European Addiction Research 24, 234-244. doi: 10.1159/000493884
  • Manthey J, Probst C, Rylett M, Rehm J (2018) National, regional and global mortality due to alcoholic cardiomyopathy in 2015. Heart, 104, 1663–69. doi: 10.1136/heartjnl-2017-312384
  • Manthey J, Stöver H, Meyer-Thompson H-G: Cannabis und Schadensminderung in Deutschland. Suchttherapie. 2018;19:148-158
  • Rehm J, Anderson P, Prieto JAA, Armstrong I, Aubin HJ, Bachmann M, Bastus NB, Brotons C, Burton R, Cardoso M, Colom J, Duprez D, Gmel G, Gual A, Kraus L, Kreutz R, Liira H, Manthey J, Møller L, Okruhlica L, Roerecke M, Scafato E, Schulte B, Segura-Garcia L, Shield KD, Sierra C, Vyshinskiy K, Wojnar M, Zarco J (2017) Towards new recommendations to reduce the burden of alcohol-induced hypertension in the European Union. BMC Med 28:173. doi: 10.1186/s12916-017-0934-1
  • Rehm J, Prieto J, Beier M, Duhot D, Rossi A, Schulte B, Zarco J, Aubin HJ, Bachmann M, Grimm C, Kraus L, Manthey J, Scafato E, Gual A (2016) The role of alcohol in the management of hypertension in patients in European primary health care practices - A survey in the largest European Union countries. BMC Family Practice 17(1); doi: 10.1186/s12875-016-0529-5
  • Kraus L, Schulte B, Manthey J, Rehm J (2016) Alcohol screening and alcohol interventions among patients with hypertension in primary health care: an empirical survey of German general practitioners. Addiction Research & Theory: 25:4, 285-92