Dr. Jakob Manthey, Dipl. Psychologe

Zentrum für Interdisziplinäre Suchtforschung (ZIS) der Universität Hamburg

c/o UKE, Klinik und Poliklinik für Psychiatrie und Psychotherapie
Martinistr. 52, 20246 Hamburg

Tel.: 040-7410-59438


seit 2019

Wissenschaftlicher Mitarbeiter am Zentrum für Interdisziplinäre Suchtforschung der Universität Hamburg (ZIS)

seit 2017

Wissenschaftlicher Mitarbeiter am Institut für klinische Psychologie und Psychotherapie, TU Dresden


Koordination epidemiologischer Daten für den „WHO Global Status Report on Alcohol and Health” im Auftrag des Centre for Addiction and Mental Health (Toronto)

2015 –  2016

Koordination der BASIS-Studie („Baseline Alcohol Screening Intervention Survey“)

2013 –  2016

Projektleiter der APC-Studie („Alcohol Dependence in Primary and Specialist Care in Europe”)

2007 – 2013

Studium der Psychologie an der Technischen Universität Dresden


  • Schadensminimierung bei Cannabiskonsum
  • Alkoholbezogene Mortalität aufgrund alkoholischer Kardiomyopathie
  • Globale Epidemiologie des Alkoholkonsums
  • Alkoholkonsumstörungen in der primären Gesundheitsversorgung




  • Kilian C, Rehm J, Allebeck P, Braddick F, Gual A, Barták M, Bloomfield K, Gil A, Neufeld M, O'Donnell A, Petruželka B, Rogalewicz V, Schulte B, Manthey J, the European Study Group on Alcohol Use and COVID-19 (2021) Alcohol consumption during the COVID-19 pandemic in Europe: a large-scale cross-sectional study in 21 countries. Addiction, https://doi.org/10.1111/add.15530
  • López-Pelayo H, Matrai S, Balcells-Olivero M, Campeny E, Braddick F, Bossong MG, Cruz OS, Deluca P, Dom G, Feingold D, Freeman TP, Guzman P, Hindocha C, Kelly BC, Liebregts N, Lorenzetti V, Manthey J, Matias J, Oliveras C, Pons MT, Rehm J, Rosenkranz M, Swithenbank Z, van Deurse L, Vicente J, Vuolo M, Wojnar M and Gual A (2021) Supporting Future Cannabis Policy – Developing a Standard Joint Unit: A Brief Back-Casting Exercise. Frontiers in Psychiatry; 12(606)
  • Kilian C, Rehm J, Allebeck P, Barták M, Braddick F, Gual A, Matrai S, Petruželka B, Rogalewicz V, Rossow I, Schulte B, Štelem?kas M, Manthey J (2021) Conducting a multi-country online alcohol survey in the time of the COVID-19 pandemic: Opportunities and challenges. Int J Methods Psychiatr Res. doi: 10.1002/mpr.1875
  • Manthey J, Kilian C, Carr S, Allebeck P, Braddick F, Gual A, Barták M, Bloomfield K, Gil A, Neufeld M, O’Donnell A, Petruželka B, Rogalewicz V, Schulte B, Rehm J (2021) Use of alcohol, tobacco, cannabis, and other substances during the first wave of the SARS-CoV-2 pandemic in Europe: a survey on 36,000 European substance users. Subst Abuse Treat Prev Policy 16, 36. https://doi.org/10.1186/s13011-021-00373-y
  • Kilian C, Manthey J, Carr S, Hanschmidt F, Rehm J, Speerforck S, Schomerus S (2021). Stigmatisation of people with alcohol use disorders: an updated systematic review of population studies. Alcoholism: Clinical and Experimental Research. doi: 10.1111/acer.14598
  • Manthey J, Hassan SA, Carr S, Kilian C, Kuitunen-Paul S, Rehm J (2021) What are the economic costs to society attributable to alcohol use? A systematic review and modelling study. PharmacoEconomics. doi: 10.1007/s40273-021-01031-8
  • Manthey J, Hassan SA, Carr S, Kilian C, Kuitunen-Paul S, Rehm J (2021) Estimating the economic consequences of substance use and substance use disorders. Expert Review of Pharmacoeconomics & Outcomes Research. doi: 10.1080/14737167.2021.1916470
  • Carr S, Rehm J, Manthey J (2021) Guidelines and reality in studies on the economic costs of alcohol use: a systematic review. The International Journal of Alcohol and Drug Research. https://doi.org/10.7895/ijadr.283
  • Kilian C, Manthey J, Kraus L, Mäkelä P, Moskalewicz J, Sieroslawski J, Rehm J (2021) A new perspective on European drinking cultures: a model-based approach to determine variations in drinking practices among 19 European countries. Addiction. doi: 10.1111/add.15408
  • Frischknecht U, Hoffmann S, Steinhauser A, Lindemann L, Buchholz A, Manthey J, Schulte B, Rehm J, Kraus L, Verthein U, Reimer J, Kiefer F (2020) Diagnostik und Behandlung alkoholbezogener Störungen – Versorgerbefragung zur Erarbeitung von Strategien der Leitlinienimplementierung. Suchttherapie, DOI 10.1055/a-1265-4687
  • Manthey J, Kilian C, Schomerus G, Kraus L, Rehm J, Schulte B (2020) Veränderungen im Alkoholkonsum in Deutschland und Europa während des (bisherigen) Höhepunkts der SARS-CoV-2 Pandemie. SUCHT, 66, 1–12
  • Manthey J, Kalke J, Rehm J, Rosenkranz M, Verthein U (2020) Controlled administration of cannabis to mitigate cannabis-attributable harm among recreational users: a quasi-experimental study in Germany. F1000Res; 9: 201. doi: 10.12688/f1000research.22612.1
  • Schulte B, Schmidt CS, Manthey J, Strada L, Christensen S, Cimander K, Görne H, Khaykin P, Scherbaum N, Walcher S, Mauss S, Schäfer I, Verthein U, Rehm J,  Reimer J (2020) Clinical and Patient-Reported Outcomes of Direct-Acting Antivirals for the Treatment of Chronic Hepatitis C Among Patients on Opioid Agonist Treatment: A Real-world Prospective Cohort Study. Open Forum Infectious Diseases, https://doi.org/10.1093/ofid/ofaa317
  • Rehm J, Kilian C, Rovira P, Shield KD, Manthey J (2020) The elusiveness of representativeness in general population surveys for alcohol Drug Alcohol Rev. doi:10.1111/dar.13148
  • Jané-Llopis E, Anderson P, Piazza M, O'Donnell A, Gual A, Schulte B, Pérez Gómez A, de Vries H,  Natera Rey G, Kokole D, Bustamante I, Braddick F, Mejía Trujillo J, Solovei A, Pérez De León A, Kaner E, Matrai S, Manthey J, Mercken L, López-Pelayo H, Rowlands G, Schmidt C, Rehm J (2020) Implementing primary healthcare-based measurement, advice and treatment for heavy drinking and comorbid depression at the municipal level in three Latin American countries: final protocol for a quasiexperimental study (SCALA study). BMJ Open, http://dx.doi.org/10.1136/bmjopen-2020-038226
  • Rehm J, Manthey J (2020) Cannabis and public health: a global experiment without control. World Psychiatry. 19:192-194. doi:10.1002/wps.20740
  • Llamosas-Falcón L, Shield KD, Gelovany M, Manthey J, Rehm J (2020) Alcohol use disorders and the risk of progression of liver disease in people with hepatitis C virus infection - a systematic review. Subst Abuse Treat Prev Policy. 2020 Jun 30;15(1):45. doi: 10.1186/s13011-020-00287-1
  • Rehm J, Kilian C, Ferreira-Borges C, Jernigan D, Monteiro M, Parry CDH, Sanchez ZM, Manthey J (2020) Alcohol use in times of the COVID 19: Implications for monitoring and policy. Drug Alcohol Rev. 2020 May;39(4):301-304. doi: 10.1111/dar.13074
  • Sornpaisarn B, Shield K, Manthey J, Limmade Y, Low WY, Van Thang V, Rehm J (2020) Alcohol consumption and attributable harm in middle-income South-East Asian countries: Epidemiology and policy options. Int J Drug Policy. 2020 Jul 22;83:102856. doi: 10.1016/j.drugpo.2020.102856
  • Probst C, Manthey J, Neufeld M, et al. (2020) Meeting the Global NCD Target of at Least 10% Relative Reduction in the Harmful Use of Alcohol: Is the WHO European Region on Track?. Int J Environ Res Public Health. 17:3423. doi:10.3390/ijerph17103423
  • Manthey J, Carr S, Rehm J (2020) Definition of a 'standard joint equivalent': Comment on "Who consumes most of the cannabis in Canada? Profiles of cannabis consumption by quantity". Drug Alcohol Depend, 1;206:107731. doi: 10.1016/j.drugalcdep.2019.107731
  • Kilian C, Manthey J, Probst C, et al. (2020) Why Is Per Capita Consumption Underestimated in Alcohol Surveys? Results from 39 Surveys in 23 European Countries. Alcohol Alcohol. 55:554-563. doi:10.1093/alcalc/agaa048
  • Manthey J, Probst C, Kilian C, Moskalewicz J, Sieros?awski J, Karlsson T, Rehm J (2020) Unrecorded Alcohol Consumption in Seven European Union Countries. Eur Addict Res. doi: 10.1159/000506333
  • Llamosas-Falcón L, Manthey J, Rehm J (2020) Changes in alcohol consumption in Spain between 1990 and 2019. Adicciones. 0:1400. doi:10.20882/adicciones.1400
  • Rehm J, Crépault JF, Wettlaufer A, Manthey J, Shield K (2020) What is the best indicator of the harmful use of alcohol? A narrative review. Drug Alcohol Rev. doi: 10.1111/dar.13053
  • Manthey J, Lindemann C, Kraus L, Reimer J, Verthein U, Schulte B, Rehm J (2020) The potential effects of an extended alcohol withdrawal treatment programme on morbidity and mortality among inpatients in the German city of Bremen: a simulation study. Subst Abuse Treat Prev Policy; 2:15. doi: 10.1186/s13011-019-0249-7
  • Manthey J, Lindemann C, Verthein U, Frischknecht U, Kraus L, Reimer J, Grün A, Kiefer F, Schulte B, Rehm J (2020) Versorgung von Personen mit riskantem Alkoholkonsum und schwerer Alkoholkonsumstörung in Bremen: bedarfsgerecht und leitlinienkonform? Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz; 63:122-130. doi: 10.1007/s00103-019-03072-z
  • Shield K, Manthey J, Rylett M, Probst C, Wettlaufer A, Parry C, Rehm J (2020). National, regional, and global burdens of disease from 2000 to 2016 attributable to alcohol use: a comparative risk assessment study. The Lancet Public Health. 5. doi: 10.1016/S2468-2667(19)30231-2.
  • Schulte B, Lindemann C, Buchholz A, Rosahl A, Härter M, Kraus L, Kiefer F, Frischknecht U, Hoffmann S, Wensing M, O'Donnell A, Manthey J, Rehm J, Schäfer I, Verthein U, Reimer J (2019) Tailored interventions to support the implementation of the German national guideline on screening, diagnosis and treatment of alcohol-related disorders: a project protocol. SUCHT; 65: 373-381
  • Kilian C, Manthey J, Moskalewicz J, Sieroslawski J, Rehm J (2019) How Attitudes toward Alcohol Policies Differ across European Countries: Evidence from the Standardized European Alcohol Survey (SEAS). Int. J Environ Res Public Health; 16: 4461. doi:10.3390/ijerph16224461
  • Manthey J, Carr S, Rehm J (2019) Definition of a ‘Standard Joint Equivalent’: Comment on “Who consumes most of the cannabis in Canada? Profiles of cannabis consumption by quantity”. Drug and Alcohol Dependence; doi: https://doi.org/10.1016/j.drugalcdep.2019.107731
  • O'Donnell A, Anderson P, Jané-Llopis E, Manthey J, Kaner E, Rehm J (2019) Immediate impact of minimum unit pricing on alcohol purchases in Scotland: controlled interrupted time series analysis for 2015-18. BMJ; 25:366 doi:10.1136/bmj.l5274
  • Rehm J, Elton-Marshall T, Sornpaisarn B, Manthey J (2019) Medical marijuana. What can we learn from the experiences in Canada, Germany and Thailand? Int J Drug Policy; 13:74:47-51. doi: 10.1016/j.drugpo.2019.09.001
  • Rehm J, Manthey J, Lange S, Badaras R, Zurlyte I, Passmore J, Breda J,
    Ferreira-Borges C, Štelem?kas M (2019) Alcohol control policy and changes in
    alcohol-related traffic harm. Addiction. doi: 10.1111/add.14796
  • Manthey J, Rehm J (2019) Mortality from Alcoholic Cardiomyopathy: Exploring the Gap between Estimated and Civil Registry Data. J Clin Med; 31: 8. doi:10.3390/jcm8081137
  • Manthey J, Rehm J (2019) Mortality from Alcoholic Cardiomyopathy: Exploring the Gap between Estimated and Civil Registry Data. J Clin Med. 31;8. doi: 10.3390/jcm8081137
  • Manthey J (2019) Cannabis use in Europe: Current trends and public health concerns. International Journal of Drug Policy; 68, 93-96
  • Ye Y, Shield KD, Cherpitel CJ, Manthey J, Korcha R, Rehm J (2018) Estimating alcohol-attributable fractions for injuries based on data from emergency department and observational studies: a comparison of two methods. Addiction, 114, 462-70. doi: 10.1111/add.14477 
  • Miquel L, Manthey J, Rehm J, Vela E, Bustins M, Segura L, Vieta E, Colom J, Anderson P, Gual A (2018) Risky alcohol use: The impact on health service use.  European Addiction Research 24, 234-244. doi: 10.1159/000493884
  • Manthey J, Probst C, Rylett M, Rehm J (2018) National, regional and global mortality due to alcoholic cardiomyopathy in 2015. Heart, 104, 1663–69. doi: 10.1136/heartjnl-2017-312384
  • Manthey J, Stöver H, Meyer-Thompson H-G: Cannabis und Schadensminderung in Deutschland. Suchttherapie. 2018;19:148-158
  • Rehm J, Anderson P, Prieto JAA, Armstrong I, Aubin HJ, Bachmann M, Bastus NB, Brotons C, Burton R, Cardoso M, Colom J, Duprez D, Gmel G, Gual A, Kraus L, Kreutz R, Liira H, Manthey J, Møller L, Okruhlica L, Roerecke M, Scafato E, Schulte B, Segura-Garcia L, Shield KD, Sierra C, Vyshinskiy K, Wojnar M, Zarco J (2017) Towards new recommendations to reduce the burden of alcohol-induced hypertension in the European Union. BMC Med 28:173. doi: 10.1186/s12916-017-0934-1
  • Kraus L, Schulte B, Manthey J, Rehm J (2016) Alcohol screening and alcohol interventions among patients with hypertension in primary health care: an empirical survey of German general practitioners. Addiction Research & Theory: 25:4, 285-92
  • Rehm J, Prieto J, Beier M, Duhot D, Rossi A, Schulte B, Zarco J, Aubin HJ, Bachmann M, Grimm C, Kraus L, Manthey J, Scafato E, Gual A (2016) The role of alcohol in the management of hypertension in patients in European primary health care practices - A survey in the largest European Union countries. BMC Family Practice 17(1); doi: 10.1186/s12875-016-0529-5